What is the primary concern when starting fluoxetine in children?

The primary concern when starting fluoxetine in children is the increased risk of suicidal ideation. This is particularly relevant because selective serotonin reuptake inhibitors (SSRIs), including fluoxetine, have been associated with a heightened risk of suicidal thoughts and behaviors in the pediatric population.

When prescribing fluoxetine to children and adolescents, close monitoring for any signs of worsening depression or emergence of suicidal thoughts is crucial. This is a guideline emphasized by health authorities, reflecting the importance of ensuring the safety and well-being of young patients during treatment.

While concerns such as hypotension, insomnia, and potential dependency are valid considerations in some contexts, they are not as directly linked to the initiation of fluoxetine therapy in children as the risk of increased suicidal ideation. Thus, prioritizing awareness of and vigilance for any changes in mood or behavior is essential in this age group.