What is the first-line medication treatment for ADHD?

Methylphenidate is considered the first-line medication treatment for ADHD due to its established efficacy and safety profile in treating symptoms of attention deficit hyperactivity disorder in both children and adults. It is a central nervous system stimulant that acts by increasing the levels of dopamine and norepinephrine in the brain, which are critical in regulating attention and behavior.

Research supports the use of methylphenidate as the primary option because it has been shown to significantly improve attention span, reduce impulsivity, and enhance overall functioning in individuals diagnosed with ADHD. Long-term studies indicate that many patients continue to benefit from methylphenidate, demonstrating not only immediate symptom relief but also sustained effects over time.

While other medications, such as atomoxetine and lisdexamfetamine, are also used in the management of ADHD, they are typically considered second-line options or are chosen based on specific patient factors. Atomoxetine, for instance, is a non-stimulant option that might be used when a patient has a history of substance use disorder or when stimulants are not tolerated well. Lisdexamfetamine is similar in action to methylphenidate but is often evaluated for patients who may respond better to amphetamines.

Sertraline, on the other hand,