What are the main risk factors associated with Clozapine?

Clozapine is an atypical antipsychotic that is notable for its unique profile and associated risks. The correct choice identifies key risk factors that healthcare providers must monitor when prescribing this medication.

One of the main risks of Clozapine is agranulocytosis, a potentially life-threatening drop in the number of white blood cells. This condition can lead to severe infections, making regular blood monitoring essential for patients on Clozapine. Due to this risk, Clozapine is usually reserved for treatment-resistant schizophrenia or when other antipsychotic treatments have failed.

Additionally, seizures are another significant risk associated with Clozapine. The likelihood of seizures increases with higher doses, and clinicians must be vigilant about this potential side effect, particularly in those with a history of seizure disorders or risk factors that could lower the seizure threshold.

The correct answer acknowledges these crucial drawbacks, which are vital for understanding the broader implications of Clozapine treatment in psychiatric settings. Understanding these risks helps in effective patient management and ensures that the benefits of Clozapine are weighed against its dangers in clinical practice.

Other choices do not accurately represent the profile of Clozapine, as they mention factors like high EPS, weight gain, or dizziness, which are not primary